Publications of Prashant D. Sonawane

Grzech, D.; Smit, S. J.; Alam, R. M.; Boccia, M.; Nakamura, Y.; Hong, B.; Barbole, R.; Heinicke, S.; Kunert, M.; Seibt, W. et al.; Grabe, V.; Caputi, L.; Lichman, B. R.; O’Connor, S. E.; Aharoni, A.; Sonawane, P. D.: Incorporation of nitrogen in antinutritional Solanum alkaloid biosynthesis. Nature Chemical Biology 21, pp. 131 - 142 (2025)

Boccia, M.; Kessler, D.; Seibt, W.; Grabe, V.; Rodriguez Lopez, C. E.; Grzech, D.; Heinicke, S.; O’Connor, S. E.; Sonawane, P. D.: A scaffold protein manages the biosynthesis of steroidal defense metabolites in plants. Science 386 (6728), pp. 1366 - 1372 (2024)

Boccia, M.; Ploß, K.; Kunert, M.; Keshan, R.; Hatam, M.; Grabe, V.; O’Connor, S. E.; Sonawane, P. D.: Metabolic engineering of vitamin D3 in Solanaceae plants. Plant Biotechnology Journal 22 (12), pp. 3389 - 3391 (2024)

Lucier, R.; Kamileen, M. O.; Nakamura, Y.; Serediuk, S.; Barbole, R.; Wurlitzer, J.; Kunert, M.; Heinicke, S.; O’Connor, S. E.; Sonawane, P. D.: Steroidal scaffold decorations in Solanum alkaloid biosynthesis. Molecular Plant 17 (8), pp. 1236 - 1254 (2024)

Kunert, M.; Langley, C.; Lucier, R.; Ploß, K.; Rodriguez Lopez, C. E.; Serna Guerrero, D. A.; Rothe, E.; O’Connor, S. E.; Sonawane, P. D.: Promiscuous CYP87A enzyme activity initiates cardenolide biosynthesis in plants. Nature Plants 9, pp. 1607 - 1617 (2023)

Sonawane, P. D.; Gharat, S. A.; Jozwiak, A.; Barbole, R.; Heinicke, S.; Almekias-Siegl, E.; Meir, S.; Rogachev, I.; O’Connor, S. E.; Giri, A. P. et al.; Aharoni, A.: A BAHD-type acyltransferase concludes the biosynthetic pathway of non-bitter glycoalkaloids in ripe tomato fruit. Nature Communications 14, 4540 (2023)

Berman, P.; de Haro, L. A.; Jozwiak, A.; Panda, S.; Pinkas, Z.; Dong, Y.; Cveticanin, J.; Barbole, R.; Livne, R.; Scherf, T. et al.; Shimoni, E.; Levin-Zaidman, S.; Dezorella, N.; Petrovich-Kopitman, E.; Meir, S.; Rogachev, I.; Sonawane, P. D.; Aharoni, A.: Parallel evolution of cannabinoid biosynthesis. Nature Plants 9, pp. 817 - 831 (2023)

Grzech, D.; Hong, B.; Caputi, L.; Sonawane, P. D.; O’Connor, S. E.: Engineering the biosynthesis of late-stage vinblastine precursors precondylocarpine acetate, catharanthine, tabersonine in Nicotiana benthamiana. ACS Synthetic Biology 12 (1), pp. 27 - 34 (2023)

Kamileen, M. O.; DeMars II, M. D.; Hong, B.; Nakamura, Y.; Paetz, C.; Lichman, B. R.; Sonawane, P. D.; Caputi, L.; O’Connor, S. E.: Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in Pseudo-Aspidosperma alkaloid biosynthesis. Journal of the American Chemical Society 144 (43), pp. 19673 - 19579 (2022)

Palmer, L.; Chuang, L.; Siegmund, M.; Kunert, M.; Yamamoto, K.; Sonawane, P. D.; O’Connor, S. E.: In vivo characterization of key iridoid biosynthesis pathway genes in catnip (Nepeta cataria). Planta 256 (5), 99 (2022)

Hong, B.; Grzech, D.; Caputi, L.; Sonawane, P. D.; Rodriguez Lopez, C. E.; Kamileen, M. O.; Hernández-Lozada, N. J.; Grabe, V.; O’Connor, S. E.: Biosynthesis of strychnine. Nature 607, pp. 617 - 622 (2022)

Sonawane, P. D.; Jozwiak, A.; Barbole, R.; Panda, S.; Abebie, B.; Kazachkova, Y.; Gharat, S. A.; Ramot, O.; Unger, T.; Wizler, G. et al.; Meir, S.; Rogachev, I.; Doron-Faigenboim, A.; Petreikov, M.; Schaffer, A.; Giri, A.; Scherf, T.; Aharoni, A.: 2-oxoglutarate-dependent dioxygenases drive expansion of steroidal alkaloid structural diversity in the genus Solanum. New Phytologist 234 (4), pp. 1394 - 1410 (2022)