Publications of Benke Hong

Grzech, D.; Smit, S. J.; Alam, R. M.; Boccia, M.; Nakamura, Y.; Hong, B.; Barbole, R.; Heinicke, S.; Kunert, M.; Seibt, W. et al.; Grabe, V.; Caputi, L.; Lichman, B. R.; O’Connor, S. E.; Aharoni, A.; Sonawane, P. D.: Incorporation of nitrogen in antinutritional Solanum alkaloid biosynthesis. Nature Chemical Biology 21, pp. 131 - 142 (2025)

Kamileen, M. O.; Nakamura, Y.; Luck, K.; Heinicke, S.; Hong, B.; Colinas, M.; Lichman, B. R.; O’Connor, S. E.: Streamlined screening platforms lead to the discovery of pachysiphine synthase from Tabernanthe iboga. New Phytologist 244 (4), pp. 1437 - 1449 (2024)

Florean, M.; Luck, K.; Hong, B.; Nakamura, Y.; O’Connor, S. E.; Köllner, T. G.: Reinventing metabolic pathways: Independent evolution of benzoxazinoids in flowering plants. Proceedings of the National Academy of Sciences of the United States of America 120 (42), e2307981120 (2023)

Sun, R.; Hong, B.; Reichelt, M.; Luck, K.; Mai, D. T.; Jiang, X.; Gershenzon, J.; Giddings Vassão, D.: Metabolism of plant-derived toxins from its insect host increases the success of the entomopathogenic fungus Beauveria bassiana. The ISME Journal 17, pp. 1693 - 1704 (2023)

Grzech, D.; Hong, B.; Caputi, L.; Sonawane, P. D.; O’Connor, S. E.: Engineering the biosynthesis of late-stage vinblastine precursors precondylocarpine acetate, catharanthine, tabersonine in Nicotiana benthamiana. ACS Synthetic Biology 12 (1), pp. 27 - 34 (2023)

Langley, C.; Tatsis, E. E.; Hong, B.; Nakamura, Y.; Paetz, C.; Stevenson, C. E. M.; Basquin, J.; Lawson, D. M.; Caputi, L.; O’Connor, S. E.: Expansion of the catalytic repertoire of alcohol dehydrogenases in plant metabolism. Angewandte Chemie, International Edition in English 61 (48), e202210934 (2022)

Kamileen, M. O.; DeMars II, M. D.; Hong, B.; Nakamura, Y.; Paetz, C.; Lichman, B. R.; Sonawane, P. D.; Caputi, L.; O’Connor, S. E.: Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in Pseudo-Aspidosperma alkaloid biosynthesis. Journal of the American Chemical Society 144 (43), pp. 19673 - 19579 (2022)

Hernández-Lozada, N. J.; Hong, B.; Wood, J. C.; Caputi, L.; Basquin, J.; Chuang, L.; Kunert, M.; Rodriguez Lopez, C. E.; Langley, C.; Zhao, D. et al.; Buell, C. R.; Lichman, B. R.; O’Connor, S. E.: Biocatalytic routes to stereo-divergent iridoids. Nature Communications 13, 4718 (2022)

Hong, B.; Grzech, D.; Caputi, L.; Sonawane, P. D.; Rodriguez Lopez, C. E.; Kamileen, M. O.; Hernández-Lozada, N. J.; Grabe, V.; O’Connor, S. E.: Biosynthesis of strychnine. Nature 607, pp. 617 - 622 (2022)

Rodriguez Lopez, C. E.; Jiang, Y.; Kamileen, M. O.; Lichman, B. R.; Hong, B.; Vaillancourt, B.; Buell, C. R.; O’Connor, S. E.: Phylogeny-aware chemoinformatic analysis of chemical diversity in Lamiaceae enables iridoid pathway assembly and discovery of aucubin synthase. Molecular Biology and Evolution 39 (4), msac057 (2022)

Trenti, F.; Yamamoto, K.; Hong, B.; Paetz, C.; Nakamura, Y.; O’Connor, S. E.: Early and late steps of quinine biosynthesis. Organic Letters 23 (5), pp. 1793 - 1797 (2021)

Rodríguez‐López, C. E.; Hong, B.; Paetz, C.; Nakamura, Y.; Koudounas, K.; Passeri, V.; Baldoni, L.; Alagna, F.; Calderini, O.; O’Connor, S. E.: Two bi-functional cytochrome P450 CYP72 enzymes from olive (Olea europaea) catalyze the oxidative C-C bond cleavage in the biosynthesis of secoxy-iridoids – flavor and quality determinants in olive oil. New Phytologist 229 (4), pp. 2288 - 2301 (2021)

Kamileen, M. O.; Hong, B.; Gase, K.; Kunert, M.; Caputi, L.; Lichman, B. R.; O’Connor, S. E.: Divergent biosynthesis of monoterpene indole alkaloids from geissoschizine. bioRxiv: the preprint server for biology (2024)

Colinas, M.; Morweiser, C.; Dittberner, O.; Chioca, B.; Alam, R. M.; Leucke, H.; Nakamura, Y.; Serna Guerrero, D. A.; Heinicke, S.; Kunert, M. et al.; Wurlitzer, J.; Ploß, K.; Hong, B.; Grabe, V.; Lopes, A. A.; O’Connor, S. E.: Independent evolution of ipecac alkaloid biosynthesis. bioRxiv: the preprint server for biology (2024)